Having worked at a large enterprise I agree that there are many good reasons not to target 'us'. However far too many companies are rocking up to sales meetings with large enterprises and have no idea about their actual needs and the scale and problems of selling to large enterprises.
Having also sold to large enterprises, you have to be willing to sometimes spend 3-6 month developing a really obscure feature that will only be used by that one customer to get the sale.
So, 3 months of up-front work. It very likely won't break any project/company, but it's enough of a drag that most people will say "fuck it" and not target large enterprises. And, well, there are plenty of other reasons not to target enterprises that the GP isn't talking about, so it may be a good choice.