We know for a fact that both the theory of General Relativity and the Standard Model are both "wrong" in the sense that they model reality piecewise with no overlapping scope, and no clear way to arrive at a unified theory that covers that gap. It's like approximating a single function with two wildly different methods, and just ignoring the bit in the middle where the two methods clearly don't agree.

Similarly, there is no consensus agreement for much of what quantum mechanics covers, despite the theory being over 100 years old and used in practical applications.