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Ask HN: Best platform to build a large website/app?

What would be the best platform to built a large website with tenth of thousands of pages and tens of thousands registered users and high traffic from scratch? The registered users could also log in and i.e. publish various stuff to the site etc.

Any advice will be appreciated. So far I am thinking about:

- PHP, HTML, CSS, Javascript & PostgReSQl

- Ruby on Rails with PostgReSQL (not sure about this one)

- not sure about Java Frameworks either

I am also thinking about hosting it in the cloud so I do not have to worry that much about the servers stuff. I would like to spend most of the time on the site development.

Your suggestions are very welcome.

( 3 comments | 2 points | on HN )
Re:Ask HN: Best platform to build a large website/app? by melvinram on Saturday October 01, 2011 @11:54PM (#3062007)
I haven't built a site with that scale but from what I understand, it can be done with pretty much all the platforms. It's more a matter of the architecture than the platform.
Re:Ask HN: Best platform to build a large website/app? by captn3m0 on Sunday October 02, 2011 @12:32AM (#3062072)
I'd recommend you to go with Ruby On Rails. It might take you some time to learn, but it would be beneficial in the long run.
Re:Ask HN: Best platform to build a large website/app? by gbaygon on Sunday October 02, 2011 @12:52AM (#3062107)
have you considered nginx, tornado, python?