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Re:Promising HIV vaccine passes phase one human trials with ... by eli on Thursday September 29, 2011 @12:48PM (#3053192)
Actually, circumcision is a proven way to reduce infection rates that doesn't involve behavior. Though, as one might imagine, it can be a tough sell in cultures where that isn't the norm.
Re:Promising HIV vaccine passes phase one human trials with ... by jules on Thursday September 29, 2011 @08:30PM (#3054957)
Circumcision has well known downsides, and its effectiveness is limited (~50%) so people would still need to wear condoms to be reasonably safe.
Re:Promising HIV vaccine passes phase one human trials with ... by eli on Thursday September 29, 2011 @09:31PM (#3055142)
Of course you should use condoms, not share needles, and get tested regularly.

But a 50% decrease in new HIV infections is huge!

Re:Promising HIV vaccine passes phase one human trials with ... by erikpukinskis on Thursday September 29, 2011 @02:50PM (#3053726)
Only amongst people who don't use condoms.
Re:Promising HIV vaccine passes phase one human trials with ... by linderspace on Friday September 30, 2011 @04:21AM (#3056187)
It can be a tough sell because it's almost always forced genital mutilation carried out on defenceless infants violating their human rights and causing irreversible damage or done by pressuring men into it without telling them the downsides.
Re:Promising HIV vaccine passes phase one human trials with ... by brendn on Thursday September 29, 2011 @03:49PM (#3053958)
Then why does the USA have the highest rate of circumcision and also the highest rate of HIV infection of developed countries? I don't think the claim holds up under scrutiny here.

[EDIT: wording]

Re:Promising HIV vaccine passes phase one human trials with ... by geebee on Thursday September 29, 2011 @04:04PM (#3054036)
Actually, this is a reasonable observation. But it actually does make sense.

My understanding is that many (all?) of these studies have been conducted in sub-Saharan africa. The environment in which AIDS spreads may be very different in developed countries. The presence of secondary infections, unhygienic conditions, and other social norms may play a big role in the spread of aids and greatly amplify the protection that circumcision provides. The evidence does look compelling.

Now, if the infection rate is already low, secondary STDs are rare, hygiene is at a very high standard, and transmission vectors are different, then the effects might be much less pronounced. I suspect it would be hard to create a controlled study of this in Europe, since you'd have to convince a large number of men who are probably in a very low risk group to be circumcised.

Re:Promising HIV vaccine passes phase one human trials with ... by brendn on Thursday September 29, 2011 @05:07PM (#3054306)
Thank you for expanding on my admittedly rushed comment. I agree that comparing health data in the US to that of developing countries is problematic. But it raises interesting questions.

One question, that I don't think has been answered sufficiently is that the controlled trials and published studies have been criticized for possibly overstating the effectiveness of treatment. (The trials were stopped early on ethical grounds which can overestimate the effects being tested.) Wikipedia has a fairly comprehensive roundup: http://en.wikipedia.org/wiki/Circumcision_and_HIV#Randomised...

I think my bigger point, though, is that it's easy to look at data and say, "Aha! This one thing is the solution" without stepping back and looking at all the different pieces that make up the big picture. It's going to take some combination of education, prevention, vaccination, and health policy to tackle this disease.

Re:Promising HIV vaccine passes phase one human trials with ... by philwelch on Friday September 30, 2011 @12:01AM (#3055615)
The US has a wide range of ethnic, cultural, and socio-economic diversity that throws off a lot of statistics when compared to other, relatively homogenous developed countries.
Re:Promising HIV vaccine passes phase one human trials with ... by eli on Thursday September 29, 2011 @05:27PM (#3054397)
You don't think which claim holds up? That circumcision cuts infection rates? As I posted in a comment below, there's a fair bit of scientific evidence to support that.
Re:Promising HIV vaccine passes phase one human trials with ... by AndyKelley on Thursday September 29, 2011 @03:16PM (#3053829)
This guy presents a fair scientific examination of whether to circumcise: http://www.youtube.com/watch?v=i2gloq-prkA
Re:Promising HIV vaccine passes phase one human trials with ... by epochwolf on Thursday September 29, 2011 @01:05PM (#3053301)
Just because infection rates are lower among males who are circumcised doesn't mean it prevents infection. http://en.wikipedia.org/wiki/Correlation_does_not_imply_caus...
Re:Promising HIV vaccine passes phase one human trials with ... by eli on Thursday September 29, 2011 @01:20PM (#3053352)