That's a great litmus test. If you find yourself working with co-founders that take their Cxx title very seriously, and you have only a couple of employees, you might have picked the wrong team.

Several of us have Cxx titles at our startup, but we sell in to really large organizations (sometimes municipal), so having "Chief Customer Happiness Officer" isn't really an option for us. Or at least we don't believe it is. In the end, it really doesn't matter, because we're all supremely confident and scared humble at the same time. None of us would hesitate to give up our titles to someone more qualified should that need or opportunity arrise.