Tweaking is usually not needed if care has been made in selecting the right hardware. In most cases things work out of the box if that selection was done correctly.

Going further, workstation tweaking is a power feature, for those that want or need it.

If you don't want to do any tweaking, my experience has been best in Fedora. out of the box it's highly usable, and unless I'm building a workstation I don't change anything. The things that I do tweak now are just settings in the "Settings" app and the gnome-tweak-tool.