Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

Re:Soybean oil affects hypothalamus, causes genetic changes ... by zhte415 on Thursday February 24, 2022 @11:30AM (#30456652)

The article specifically mentions, following that cited part, on Linoleic acid:

> the research team has not yet isolated which chemicals in the oil are responsible for the changes they found in the hypothalamus. But they have ruled out two candidates. It is not linoleic acid, since the modified oil also produced genetic disruptions; nor is it stigmasterol, a cholesterol-like chemical found naturally in soybean oil.

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Re:Soybean oil affects hypothalamus, causes genetic changes ... by simonsarris on Thursday February 24, 2022 @11:48AM (#30456945)

But the team DID note that "the SO + CO diet caused more weight gain over the 16-week study than the other HFD" (As opposed to the modified soybean diet). This is a quote from the paper, not the article.

According to the paper the Linoleic acid composition of the oils in question are:

    soybean:     %52.90
    modified SO:  %7.42  (aka plenish)
    coconut:      %0.06

So while some of the genetic expressions may exist in both, both have LA, and the higher LA = higher obesity according to the paper authors (they did not give a graphic for the obesity differences, unfortunately)

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Re:Soybean oil affects hypothalamus, causes genetic changes ... by forgetfulness on Thursday February 24, 2022 @11:36AM (#30456719)

It explains why they chose coconut oil for the comparison, it has one of the least amounts of linoleic acid in its composition in any fat.

Ironically, lineseed oil is also low in linoleic acid.

https://www.news-medical.net/health/Oils-Rich-in-Linoleic-Ac...

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