This would also go nicely with arbitrary-width integers. Load/store instructions would just need to set aside a few opcode bits to define the number of bits to load or store, and pointers would just get 3 bits wider (basically left-shifted 3 bits, the upper bits in a 64-bit pointer are not used anyway). Pointer alignment could be the same as the bit width, e.g. 2-bit load/store could require 2-bit alignment, byte load/store byte alignment, and so forth...