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Re:Ask HN: How to raise funds for rare disease research? by blfr on Tuesday February 08, 2022 @02:17AM (#30255742)
> Both. We're not even close to our limits on research capacity.

Really? From the outside it seems to me like we are beyond our limits on research capacity.

The progress seems to be slowing down everywhere while the price per discovery of a new drug skyrockets with many having rather disappointing efficacy (high NNTs).

Re:Ask HN: How to raise funds for rare disease research? by JoshTriplett on Tuesday February 08, 2022 @02:35AM (#30255821)
None of those limitations seem inherent, nor are we close to the societal limits for what we can do when we actually care about accomplishing something. We may be somewhat close to the limits of what we can do with current R&D structures and incentives, but that's quite different.