Ask HN: How to raise funds for rare disease research?

Re:Ask HN: How to raise funds for rare disease research? by netizen-936824 on Monday February 07, 2022 @08:13PM (#30253809)

So you're taking all wet bench data and analyzing or integrating it rather than modeling? That's interesting!

Are there any possibilities that you see from your experience in using modeling or other in silico methods to reduce time in the lab, find new leads in drug development, or otherwise enhance research capabilities?

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Re:Ask HN: How to raise funds for rare disease research? by codekilla on Monday February 07, 2022 @08:54PM (#30254049)

Yes, essentially, though you may create models of interactions etc., but the main idea is to extract information from various aspects of the cell.

As far as in silico, I think absolutely there are probably opportunities here. Generative models might be useful for some type of counterfactual (automated) reasoning with respect to disease course/treatment. I think we're in the relatively early days of collecting high resolution cellular data, so I think in silico approaches like this will be more and more relevant.

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