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A comment on What the Omicron wave is revealing about human immunity. Parent comment
https://wwwnc.cdc.gov/eid/article/27/9/21-1042-f2
And the virus contains immune evasion genes like ORF8 which evade humoral immunity responses by downregulating MHC-I:
https://www.pnas.org/content/118/23/e2024202118
Nobody in their right mind would produce a vaccine with ORF8 in it since it defeats the whole purpose of stimulating T-cell and B-cell recognition.
There's good reasons why natural immunity has been downplayed.
https://wwwnc.cdc.gov/eid/article/27/9/21-1042-f2
And the virus contains immune evasion genes like ORF8 which evade humoral immunity responses by downregulating MHC-I:
https://www.pnas.org/content/118/23/e2024202118
Nobody in their right mind would produce a vaccine with ORF8 in it since it defeats the whole purpose of stimulating T-cell and B-cell recognition.
There's good reasons why natural immunity has been downplayed.