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A comment on Moderna’s HIV vaccine has officially begun human trials. Parent comment

Re:Moderna’s HIV vaccine has officially begun human trials by Vrondi on Monday January 31, 2022 @01:24PM (#30151871)
But, HIV mutates super easily, which is why we do not already have a more traditional vaccine that works. It will be a greater challenge in this regard than COVID-19/Omicron, not an easier one.
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Re:Moderna’s HIV vaccine has officially begun human trials by woodruffw on Monday January 31, 2022 @01:28PM (#30151920)
Two observations:

1. Given the continued efficacy of the COVID-19 vaccines against severe illness, it stands to (lay-)reason that a similar outcome might occur with HIV. A world in which HIV is roughly as transmissible as it currently is (and is still responsive to other avenues of treatment/prevention, like PrEP) but where it does not cause fatal immunocompromization is an extremely preferable world.

2. We have no particular reason to believe that HIV's mutation vectors are more or less susceptible to the vectors that mRNA vaccines target, versus "traditional" vaccines.

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