What could Malone do that would lead to legal payouts like these?[1][2] Are Malone's misleading claims comparable to those of Pfizer's regarding Bextra, for instance?

I also have to wonder how "tight and regulated" they are that these payouts in the hundreds of millions or even billions end up in court, repeatedly, for actions that look remarkably similar.

I simply don't know what your objection to Malone's words could be if your going to take the position you have on Pfizer.

[1] https://en.wikipedia.org/wiki/Pfizer#Legal_issues

[2] https://en.wikipedia.org/wiki/Franklin_v._Parke-Davis