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Re:Quarto: A scientific and technical publishing system buil... by ivan_ah on Sunday January 23, 2022 @08:43PM (#30052695)
Have you looked at jupyter-book?

The "native" format is MyST, which is markdown with extra things added in to customize behaviour of code blocks: https://jupyterbook.org/reference/cheatsheet.html

I've been writing some stuff in MyST and I found it very productive. The ability to also support jupyter notebooks is also interesting.

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