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Re:Alphabet's Calico has begun trials on a molecule for neur... by dghughes on Friday January 21, 2022 @06:54PM (#30031548)
Not even research chemicals my Dad had IPF and from what I could find Metformin was a promising off-label cure. But there was no way to try it. People get desperate sometimes not even the people who are sick but their caregivers.

My dad passed away April 21, 2021 on my birthday.

Re:Alphabet's Calico has begun trials on a molecule for neur... by ipsum2 on Friday January 21, 2022 @08:00PM (#30032000)
Sorry for your loss. Did you or your dad tried talking to doctors for a prescription? Metformin is a very common drug and has a safe profile, some doctors would be able to prescribe it off-label.
Re:Alphabet's Calico has begun trials on a molecule for neur... by dghughes on Saturday January 22, 2022 @10:27AM (#30037484)
Thank you. And yes I even printed off some peer-reviewed studies about IPF and Metformin for Dad to take with him to the doctor. The doctor would "look into it" but I suspect that Dad who was not great at anything technical would have agreed with the doctor and not challenged him.

My mother has type 2 diabetes so Metformin was right there in the house. It's infuriating to think Metformin could have made Dad's life better. Maybe not cure him but at least help a tiny bit.

The other problem severely ill people who have been sick for years give up before they even know it. I saw it in Dad but I couldn't see the effects of anxiety which was also there until it was too late. Anxiety is what eventually killed him more than his disease.