This professor of energy policy thinks it is making a difference: “The end of nuclear power in Germany will likely push prices up even further, according to Sebastian Herold, a professor of energy policy at the Darmstadt University of Applied Sciences” (https://www.france24.com/en/live-news/20211231-germany-to-cl...)

When you lose 25% of your 2011 energy producing capacity by closing many nuclear power plants, it’d be strange if there was no effect. The pollution increase is even more worrying after many new studies since then found negative effects on human health that we didn't know about earlier: https://www.heinz.cmu.edu/media/2020/January/study-examines-...