A philosophical perspective - Ask yourself this:"why do you want to start a startup?" Is it to make $? fast and lots of it? If so, then just rehash old startups and make a new one with a twist (another photosharing app, file sharing app, etc) - new startups today are all a mish-mash of some sort. If $ is not your immediate answer, then it must be drive/passion - something you want to answer/see because no one else has that is disruptive. In all honesty,the "next" big thing will take time and patience and you will need your drive and passion to keep it going. Other 2 things I want to add: think outside the box - step back and look at it from another way that no one else has; don't stay complacent with the status quo. And, finally, take calculated risks. Good luck.