But what about other chemicals, Glycine contributes to an increase in 5alpha Reductase which helps reduce Cortisol one of the stress hormones. It can be used in place of sugar in hot beverages and food, how much does stress contribute to depression? https://en.wikipedia.org/wiki/5%CE%B1-Reductase#List_of_conv...
And then there is Glutathione which increases light sensitivity, could this help reduce Seasonally Affect Disorder (SAD) also known as the winter blues, knowing that it also helps management of ROS, peroxides, lipid peroxides and heavy metals? Glutamine, N-Acetyl Cysteine and Glycine help to increase Glutathione in the body.
I wonder if fMRI has a similar effect on the brain to homogenising milk, namely it softens the fat walls in milk. Is fMRI having an effect in the brain or in the vascular system with plaques that contribute to atherosclerosis, because induction hobs or magnetic induction reduces inflammation https://peerj.com/articles/929.pdf does this demonstrate that depression is caused by a variety of factors not just one's linked to serotonin even though serotonin plays a part with the immune system?
Who says it won't last? Most depressions actually do get better by themselves.
How do you think humanity has survived so far?
(Most, but not all. And even if it eventually gets better without meds, there was still a lot of suffering.)
No clue whether it's the depression itself, or whether that's just a side-effect of something else that's useful.
Empirically, most clinical depressions get better by themselves today.
Similarly, most alcoholics improve by themselves.
(Of course, effective treatment is still useful!)
From the article further on.