You make a great point about animal reservoirs, but the transmission bandwidth between humans and animals is afaik much lower than between humans. If you accept this assumption, and if we also assume that we really wanted to eradicate this thing, we could limit human transmission such as to reduce Rt well below 1 by implementing well-coordinated and strict policies.

Then you're left with the "leaky bucket" of transmission between humans and animals... But this is a known vulnerable point which could be monitored effectively and very cheaply.

Here in Canada, we've been trying to eradicate rabies from the wild for half a century or so now. There are orally-active rabies vaccines we litter the landscape with in edible treat format. We cull rabid animals and quarantine or cull their known animal contacts. It's common knowledge that exposure to possible vectors means you need to go to the hospital. Tens of thousands of people are treated preventatively each year.

Despite all this, human cases of rabies still happen. Fortunately it's rather hard to spread rabies between humans and it's symptomatic by the time it becomes infectious. In the case of an easily airborne virus even with such measures available like vaccination and prophylaxis for possible exposure, it seems daunting to the point of impossible even in a very wealthy country. In the developing world it would be certainly hopeless.

Yeah, eradication of a disease in the wild is a whole other matter. But so rabies also is another matter. Cases are relatively rare here (hello, fellow Canadian!), and surveillance is relatively good for the little burden of disease it brings.

https://www.canada.ca/en/public-health/services/diseases/rab...

Genetic surveillance is just around the corner, and will soon be / is now within reach even of developing countries, with solutions like Oxford Nanopore's ultra-portable sequencers.

https://www.youtube.com/watch?v=6RRSxWtJPUw

This is completely unrealistic. Effective continuous monitoring for animal to human transmission would never be cheap. In much of the developing world it's not even remotely feasible. Have you ever been to places like rural Mexico?

The virus is here to stay. Eradication is a total fantasy, just a distraction and waste of time.