Telomerase - an Enzyme found in Gamete and Stem (and Tumor!) Cells can reverse this Telomere shortening. Cycloastragenol derived from Astragalus herb can supposedly activate Telomerase - unfortunately it's very expensive to extract in significant quantities eg TA-65 costs $800 for 90 capsules. I tried it for a while and definitely noticed an effect, better skin, vivid dreams more energy. High cost and some concern over potential for Tumor promotion put me off continuing.