Sure, the few remaining quality papers can (and do) introduce local editions for markets other than their "traditional" home base. Unfortunately, the economics aren't much different than they are for the regional paper that previously covered the area.

I say "not much" because there might be a chance that people would appreciate the combination of local news combined with the national and international coverage that would be shared among all these editions. But that, also, isn't exactly new: it's what these "newspaper chains" have been doing for at least 20 years.