I use it as my primary OS. You have to do more setup work, there’s much less documentation/help online than more popular distros, and running proprietary software (which usually links to glibc) is probably not worth the effort. This is mostly fine for me, as I don’t do much on my computer aside from code and use a web browser — the only difficulty is most streaming video unfortunately requires Widevine. Given those limitations, I’m very happy with it: it’s very simple and I have a much better understanding of what is installed/running and why.