Yes, but there is a difference between an attack being run by a low level hardware hacker vs. the software being run by average users. This is why I said it would be hard, you would need to encode a lot of low level hardware knowledge into your application.

This might only be useful in very specialized circumstances, like with kernel support on only a handful of carefully chosen hardware platforms. However, someone like Apple could do this on their systems, as they control both the kernel and the hardware. Sensitive memory locations could be cordoned off in special zones with buffering to prevent Rowhammer type attacks.