There is a specific belief here around something which changes under these substances, around memory, recall, ideation, I'd use the word "plasticity" but thats not what I mean. Taking these drugs (or MDMA) and undergoing some kind of guided psychological engagement, appears to have lasting effects on how mood is mapped over experience, for people suffering negative ideation/PTSD.

I'd love to poo-poo this because I believe in (and do) CBT and have a continuing high level engagement with somebody which is strongly anti-drug: the SSRI are a weapon for a problem which are being over-used. Its classic hammer/nail analogy stuff.

There was interesting, good science being done on these drugs before the "war on dope" took everything offline.

Consider the work on its effect on timor mortis. If we can ease people's passage into an inevitable end, Isn't that net-beneficial overall?