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Re:Pfizer's oral Covid-19 antiviral cuts hospitalization, de... by swader999 on Friday November 05, 2021 @11:48AM (#29120967)
I think Delta is still above r0 1 in vaccinated. Delta plus is worse. So there will be spread amongst vaccinated. Not as much as unvaccinated but with vaccinated conditioned to think they are safe I don't see it solving much in the medium to longer term.

A high population of vaccinated is mathematically more likely to produce more virulent strains with a non sterile vaccine in a fast mutating virus.

Re:Pfizer's oral Covid-19 antiviral cuts hospitalization, de... by jayknight on Friday November 05, 2021 @12:50PM (#29121803)
> A high population of vaccinated is mathematically more likely to produce more virulent strains with a non sterile vaccine in a fast mutating virus.

Not so. Lots of cases produce worse variants, not vaccines.

https://theconversation.com/massive-numbers-of-new-covid-19-...

Re:Pfizer's oral Covid-19 antiviral cuts hospitalization, de... by nradov on Friday November 05, 2021 @01:55PM (#29122610)
That's possible but unproven. The current thinking is that new variants are mostly likely to evolve in immunocompromised patients who experience persistent infections. Vaccines are less effective in such patients because the immune system doesn't respond as it should.

https://www.scientificamerican.com/article/covid-variants-ma...

Re:Pfizer's oral Covid-19 antiviral cuts hospitalization, de... by MisterMower on Friday November 05, 2021 @02:39PM (#29123173)
But if vaccines permit asymptomatic spread, meaning the virus enters a host and begins replicating, without the host showing symptoms, by definition you’re increasing the number of opportunities for new mutations to occur. I’m not sure how that article refutes the grandparent comment’s point.
Re:Pfizer's oral Covid-19 antiviral cuts hospitalization, de... by jayknight on Friday November 05, 2021 @03:35PM (#29123816)
Asymptomatic spread is possible with or without the vaccine, but significantly less with it.
Re:Pfizer's oral Covid-19 antiviral cuts hospitalization, de... by swader999 on Friday November 05, 2021 @06:27PM (#29125394)
Its much more possible with a vaccine that reduces the severity of the disease and permits people to still be out and about, perhaps even unaware they might be infectious. If it puts you on your ass or worse, you aren't out spreading it.