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Re:The Clock Frequency of our Universe by shabble on Saturday August 20, 2011 @04:22AM (#2906169)
Permutation City[1] by Greg Egan is one particular (hard SF) look at this idea.

I'm pretty sure there are others, it's quite a common trope.

In the (hopefully) real world, there was something fairly recently about possible violations of the Planck length: http://www.sciencedaily.com/releases/2011/06/110630111540.ht... (news wrapper around http://arxiv.org/abs/1106.1068 )

[1] http://www.amazon.com/Permutation-City-Greg-Egan/dp/00610548...

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