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A comment on Post-SSRI sexual dysfunction. Parent comment

Re:Post-SSRI sexual dysfunction by gtirloni on Thursday October 28, 2021 @10:26PM (#29034505)
Does it mean they don't also inhibit LSD effects like Venlafaxin does?
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Re:Post-SSRI sexual dysfunction by notmymainlogin on Friday October 29, 2021 @04:21AM (#29036433)
I can tell you from first hand experience that Venlafaxine does not inhibit the effects of LSD in all people. It might in some, but certainly not in all. I have one data point.

Also, it does limit, if not entirely mask, the effects of some common recreational dopamine reuptake inhibitors.

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Re:Post-SSRI sexual dysfunction by heavyset_go on Thursday October 28, 2021 @10:55PM (#29034683)
LSD activates 5HT2A. Mirtazapine is the only medication I posted about that blocks 5HT2A.

I'm not sure what the mechanism behind venlafaxine's blunting effect on LSD is.

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