Yup, there are a lot of people with chronic pain, and the only things that reliably treat pain without being really bad for your system are opiates and weed. Paracetemol (and to a lesser degree ibuprofen) are so bad for you they mix it into opiates so that if you take enough to get high the paracetemol sends you to hospital, and weed is stigmatised at best, and still illegal in most of the world. Ketamine in useful doses has too strong side effects, cocaine-derivatives are only really good locally, and also not great for your system. And that's about all we've got.

As a kid I had migraines, and quickly developed an immunity to the pain-relieving aspect of paracetemol, they were basically candy by the time I was a teenager. Luckily they disappeared in my late teens, but now I'm in my 40s and I get weird pains they call "cluster headaches" in my face. I did some tests, got an MRI, and they didn't turn up anything, which is pretty much the end of medicine, pain management is all there is for me. In Australia we need a prescription for any opiates, so I have to be treated like a drug addict to get painkillers the rest of the world can buy over the counter, it's a disgrace.