Lost limbs, burns, skin conditions, non-contagious hacking coughs, every neurological motor disease (which cause strange movements), many sensory conditions (which result in lack of awareness and awkward moments), cognitive conditions which usually result in strange behavior, in one way or another... I have a hard time imagining an illness that would increase people's desire to be around you. The unpleasant reality is that the herd wants to eliminate its weaker members, and we can either embrace that and end up like the Nazis (who exterminated people with physical imperfections and encouraged people who fit their narrowly construed "normal" to breed), or we can resist that part of our nature and be reasonable and kind. Not every part of human nature is good; all evil is done by humans, and everything that humans do is in one way or another a facet of human nature.

There's no clear distinction between the innate desire to get rid of trans people and the innate desire to get rid of anyone who isn't physically or mentally what we're used to, or even the desire to hang around beautiful and intelligent people and leave the ugly ones out. Consequently, it deserves a lot of self-reflective skepticism - because we already know that many of the other behaviors it leads to are harmful even to those who practice them, and beyond that to those who suffer from their practice.