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A comment on Exome sequencing and analysis of 450k UK Biobank participants. Parent comment

Re:Exome sequencing and analysis of 450k UK Biobank particip... by flobosg on Wednesday October 20, 2021 @09:10PM (#28939026)
FWIW the study focuses on the coding region of the human genome, i.e., the other 2%.

It is also important to point out that the fraction of non-coding DNA in a genome depends on the organism and is not correlated to complexity. There are multicellular organisms with less than 5% of it as well as unicellular organisms with amounts of DNA orders of magnitude higher than humans.

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Re:Exome sequencing and analysis of 450k UK Biobank particip... by adolph on Wednesday October 20, 2021 @09:14PM (#28939050)
the marbled lungfish has the largest recorded genome of any eukaryote. One haploid copy of this fish's genome is composed of a whopping 132.8 billion base pairs, while one copy of a human haploid genome has only 3.5 billion

http://www.nature.com/scitable/topicpage/eukaryotic-genome-c...

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Re:Exome sequencing and analysis of 450k UK Biobank particip... by scrollaway on Wednesday October 20, 2021 @09:49PM (#28939344)
DNA developers these days just use electron and don’t care about efficiency. That lungfish is ripe for a refactoring.

Bet I could implement a new lungfish with only a few million base pairs in a weekend.

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Re:Exome sequencing and analysis of 450k UK Biobank particip... by flobosg on Wednesday October 20, 2021 @09:52PM (#28939364)
640 kbp should be enough for anybody.
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Re:Exome sequencing and analysis of 450k UK Biobank particip... by yellowcake0 on Thursday October 21, 2021 @01:31AM (#28940696)
Is electron some sort of synthetic genome compiler?
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Re:Exome sequencing and analysis of 450k UK Biobank particip... by richeyryan on Thursday October 21, 2021 @04:56AM (#28942018)
To be specific, it is Javascript based desktop application platform. Each finished app ships its own version of Chrome which affects the size and arguably adds quite a lot of overhead. It also makes developing cross-platform desktop applications much more accessible, thus making it easier for more developers to make slow, unoptimized applications. Overall it has become a meme for bulky, slow desktop apps with Visual Studio Code being the notable exception.
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Re:Exome sequencing and analysis of 450k UK Biobank particip... by ComputerGuru on Thursday October 21, 2021 @02:12AM (#28940961)
It’s a (not well executed) joke about electron’s memory consumption and how developers refuse to use anything better.
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Re:Exome sequencing and analysis of 450k UK Biobank particip... by scrollaway on Thursday October 21, 2021 @07:09AM (#28942805)
> not well executed

Aw! :(

For the record I like Electron a lot and am usually the one to defend it on HN, but it indeed was a comment on binary size, needless duplication and copy-paste culture ;)

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Re:Exome sequencing and analysis of 450k UK Biobank particip... by Zababa on Thursday October 21, 2021 @04:10AM (#28941715)
I think the joke may be about binary size and not memory, which would make sense when talking about DNA.
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