Availability has never been an issue for me (living in Germany), what annoys me though is that I have to switch stores (US to Germany) and search the book due to the lack of a direct link.

OCR errors are quite rare, if you buy a "real" book you get typos etc. as well sometimes I don't see why this would be very annoying.

I don't like DRM from an ideological standpoint however I daily life it is really only an issue if you want to lend something and Amazon allows it, the publishers don't but that is a different issue.