What should we expect when we are pushing any disagreement whatsoever out of the mainstream? I was vaccinated the day I was able to be, but if I started browbeating everyone else around me who was slower, they'd just cut off contact and start associating with people who weren't total jerks to them.

If the only ones who are listening to the disagreeing moderates are radicals, we should expect an increase in radicalization.

Are you saying that it's the fault of the groups not directly present, we can blame the moderates who aren't there?

You'll either eject the cranks or become them. The (possibly apocryphal) tale is "As we say in Germany, if there’s a Nazi at the table and 10 other people sitting there talking to him, you got a table with 11 Nazis."

This dynamic has happened many many times on the left, with the far left cranks.