Re:The curious DNA circles that make treating cancer so hard
by toomuchtodo on Saturday October 02, 2021 @06:39PM
(#28732747)
How do you improve the immune system to convey the improvements we’ve made with mRNA to it?
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Re:The curious DNA circles that make treating cancer so hard
by jcims on Saturday October 02, 2021 @06:48PM
(#28732797)
We haven't really made any improvements to the immune system with mRNA, we're just giving it some training film to be ready when the fight comes.
An immune system that has a hair trigger to new antigens would likely cause more problems than it solves. Some kind of ability to have contagious antibodies might be an actual improvement but the fact that we don't see that in nature tells me it has downsides that are difficult to see.
Re:The curious DNA circles that make treating cancer so hard
by KMag on Saturday October 02, 2021 @07:38PM
(#28733181)
> Some kind of ability to have contagious antibodies might be an actual improvement but the fact that we don't see that in nature tells me it has downsides that are difficult to see.
My biology education is a bit weak, but off the top of my head, autoimmunity being contagious sounds like a likely side-effect of contagious antibodies.
Re:The curious DNA circles that make treating cancer so hard
by tiborsaas on Sunday October 03, 2021 @05:15AM
(#28735692)
We could sample the actual cancer in the patient and custom print an mRNA cure to that specific person for maximum accuracy.
The Pfizer/BioNTech vaccine was created in hours after Covid was sequenced. So this might not be a too far fetched idea.
Re:The curious DNA circles that make treating cancer so hard
by DrAwdeOccarim on Sunday October 03, 2021 @08:54AM
(#28736825)
Easier said than done, but yes most mRNA companies are trying the non-personalized and personalized cancer vaccine idea. The issue is the immune system is held back, like a big bouncer holding you back in a fight. Checkpoint inhibitors remove that bouncer, but now you're drunk and throwing fists all over the place, hitting both your friends, the bouncer, and the hooligans at the same time...