To get rid of abstractions you almost should be writing more directly in some sort of COM+ language.
(To explain the punchline for those that don't catch the joke: COM+ was the codename/early name of what became .NET.)
The funny part is OP is talking all about uOPS when if he was really hardcore (like I am) he'd know that these dlls in turn call ntdll, many calls in ntdll are undocumented but much faster than their wrappers in the other dlls. But no sane person is going to strictly do ntdll calls except for the most performance critical code.
OP just doesn't know enough about C and C++, he probably grew up on C++ and forgot about the old C apis. I used to reverse engineer and delve deep into the windows API. I know a little bit more about performance than the average high level programmer.
And ultimately, .NET does a fine job with performance. C++ coders crapping all over .NET should take a look at the Objective C API of Apple. It's the default and every Objective C call incurs overhead and is basically a wrapper around the undocumented C API. But I don't think anyone ever complained about this abstraction, because it's such a stupid and small amount of performance to harp about. The convenience outweighs the tiny little uOPS loss.
This is why it’s very difficult to have conversations. Most programmers really don’t even know how computers work.
Here is a real kernel: https://news.ycombinator.com/item?id=7958194
It's so difficult to have conversations with engineers that don't know x86 assembly. They never stop complaining. If only I could NOP them! ;-)
In these situations it is common to have a problem that is really easy to solve but the API abstractions you have to work with doesn't support the operations at the speeds you need to solve it. If you have never experienced that then you aren't working on performance intensive projects where every bit counts and your input on this topic doesn't matter. I have worked on performance intensive libraries crossing programming language boundaries and the abstraction boundaries absolutely puts a limit on the amount of performance you can get. Well designed abstractions are less obstructive but plenty of them aren't well designed and even the well designed ones have overhead.