News for hackers. Stuff that matters.
Re:DEA Still Insists Marijuana Has No ‘Accepted Medical Use' by stooliepidgin on Wednesday September 29, 2021 @10:52PM (#28702666)
Placebo effect. CBD and THC are not well absorbed topically and there's no data on transdermal bioavailability, so the effective dosage would be unscientific and unknown. The majority of CBD creams fall within the category of snake oil to dupe consumers into spending money just as they do on beauty products. THC absorption by the skin is very low.

https://pubmed.ncbi.nlm.nih.gov/12100860/

Re:DEA Still Insists Marijuana Has No ‘Accepted Medical Use' by risedotmoe on Thursday September 30, 2021 @08:54AM (#28705733)
While some CBD products I do believe to be snake oil, what basis do you have for products containing both CBD and THC to only being effective as a placebo? CBD isn’t truly effective without THC and the THC is what basically turns the snake oil into a legitimately effective product. Additionally, everyone’s sensitivity to marijuana differs and while skin absorption may be “low” that does not mean none and even the effects of a low amount can be felt.
Re:DEA Still Insists Marijuana Has No ‘Accepted Medical Use' by stooliepidgin on Sunday October 03, 2021 @06:13PM (#28740958)
> what basis do you have for products containing both CBD and THC to only being effective as a placebo

Read the article. Because without carrier molecules, cannabinoids cannot be effectively absorbed to do much more than provide minor, dermal-area effects. There's no getting high, and not much deep penetration of anything.

> CBD isn’t truly effective without THC.

Truly what? Based on what evidence? 10 mg of pure CBD in a lipid sublingual tincture is calming if you've ever tried it. Easily distinguishable from placebo.