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Re:Johnson and Johnson says its Covid booster shot provides ... by javagram on Tuesday September 21, 2021 @10:34AM (#28605397)
I’ve got to think they’ll develop a 2nd generation vaccine with fewer side effects especially if a new one is actually needed yearly (still not convinced we don’t just need the vaccine re-tuned for Delta rather than blindly shoving booster after booster of the original strain).

I get the flu shot every year and have zero side effects, it’s a different type of vaccine but I believe the Chinese have developed an inactivated virus vaccine for covid.

Re:Johnson and Johnson says its Covid booster shot provides ... by basch on Tuesday September 21, 2021 @10:48AM (#28605560)
Part of it is just dose. Moderna had different Phase 3 trials than Pfizer and didnt hone in on dose as much, so its shot was probably overkill. But seeing how it now seems to have more longevity, maybe that overkill comes with a bonus staying power.

Im not sure it quite works that way but maybe it really is as simple as "less more often" = fewer side effects, "more less often" = more side effect, less often"