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Re:High genetic barrier to SARS-CoV-2 polyclonal neutralizin... by Larrikin on Monday September 20, 2021 @05:59PM (#28599563)
No vaccine is 100% effective and it is unethical to purposefully expose people to disease.
Re:High genetic barrier to SARS-CoV-2 polyclonal neutralizin... by sarpeedo on Monday September 20, 2021 @06:22PM (#28599805)
Before Chicken Pox vaccination was invented people would hold "Pox Parties" to infect and immunize their children at a young age when risk of severe infection was low.

https://en.wikipedia.org/wiki/Pox_party

Re:High genetic barrier to SARS-CoV-2 polyclonal neutralizin... by gfodor on Monday September 20, 2021 @06:04PM (#28599609)
Huh? The ethics of therapies that expose people to pathogens is complicated - many examples where exposure can be ethical as long as patient is aware of the risks. Arguably all vaccines fall into this ethical framework, and other immunizations which involve exposure.
Re:High genetic barrier to SARS-CoV-2 polyclonal neutralizin... by somewhereoutth on Monday September 20, 2021 @07:08PM (#28600178)
I'm unclear about these muddled responses to your post that simply states two incontrovertible truths.
Re:High genetic barrier to SARS-CoV-2 polyclonal neutralizin... by oskarpearson on Monday September 20, 2021 @06:12PM (#28599693)
Re:High genetic barrier to SARS-CoV-2 polyclonal neutralizin... by dcow on Monday September 20, 2021 @06:05PM (#28599620)
Under what ethical framework?
Re:High genetic barrier to SARS-CoV-2 polyclonal neutralizin... by sasquatch69 on Tuesday September 21, 2021 @11:38AM (#28606121)
10x to 100x less likely but still a distinct possibility you kill someone that would've lived if they weren't inoculated with a live virus. That's messed up by itself, but also cases like that would likely discourage the people on the fence about vaccination.

https://www.nytimes.com/interactive/2021/08/10/us/covid-brea...

Minor live infections to build immunity is called variolation, it's a tactic that was used effectively historically against smallpox, but effectively got obsoleted by vaccination, which doesn't kill as many people.

https://en.wikipedia.org/wiki/Variolation

Re:High genetic barrier to SARS-CoV-2 polyclonal neutralizin... by dcow on Wednesday September 29, 2021 @03:08PM (#28698397)
You linked data on breakthrough infections. Those are infections in people who have been vaccinated, some of which can still result in death. I don't believe there have been any reported deaths from the vaccine. There may be an alleged one, but the details are controversial. If you can link data suggesting that the vaccine is 10x to 100x less likely than covid to kill you but does still reliably kill you, I think we could entertain this line of rhetoric further.

Despite that, let's concede the vaccine does kill people: I'm not sure that's unethical though if more people end up dead because the population didn't quickly achieve immunity and stop the spread of the virus. There are a lot of ethical frameworks out there and in the US we are actually a majority rule so as a society we should generally be protecting the interests of the majority of people except in cases where it leads to sever oppression or breach of civil liberties. We are okay with the draft (forced risk of death) during times of war yet somehow when the enemy is unfamiliar in the form of a virus we aren't?

Re:High genetic barrier to SARS-CoV-2 polyclonal neutralizin... by disambiguation on Monday September 20, 2021 @06:19PM (#28599778)
yet this exactly what the pharma companies did during the clinical trials to confirm the vaccines' efficacy.
Re:High genetic barrier to SARS-CoV-2 polyclonal neutralizin... by IX-103 on Monday September 20, 2021 @09:02PM (#28600954)
Wait, what? No. Just no.

To confirm efficacy they gave the vaccine to half of a population likely to develop the disease naturally. Then they compared how many people for sick in each group. That's why testing took a year instead of 2 months, they have to wait for enrollees to get sick naturally.

If we ignore ethics, I guess we could get more nuanced efficacy information out of a small sacrificial population. But that is just not done. Not even during a pandemic.