Its really offensive to me that many in the research community seem to prioritize publication count and reputation over meaningful research. This is antithetical to the practice science, and stymies progress by forcing entire fields into stagnation and dead ends. How long have we been chasing the amyloid plaque hypothesis, for example?

Perhaps my opinion would be different if my livelihood depended on my paper count, but if that's the case then maybe it's time for a realignment of incentives in academia, not to imply that such a cultural shift would be trivial...