Engineers grow pancreatic organoids that mimic the real thing

Re:Engineers grow pancreatic organoids that mimic the real t... by mleonhard on Tuesday September 14, 2021 @02:51AM (#28521200)

The new treatment isn't an immuno-suppressant. It de-programs the immune system so it stops attacking the beta cells. It's essentially a highly-effective allergy shot.

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Re:Engineers grow pancreatic organoids that mimic the real t... by Benjamin_Dobell on Tuesday September 14, 2021 @03:08AM (#28521305)

Thanks for the clarification. Your links aren't working now (site maintenance).

However, I did view them initially. The study abstracts mentioned immunotherapy, I didn't even realise we were capable of "de-programming", or that that was a considered immunotherapy!

My 3 year old daughter is the Type 1 diabetic in our family. However, I'm immunosuppressed due to a (seemingly) entirely unrelated autoimmune disease, Sarcoidosis. I'll definitely be keeping an eye out for this more targeted approach to immunotherapy.

If you happen to have links to any other papers/articles using similar techniques (even for different diseases) then I'd be quite curious to read up on the topic. Thanks!

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Re:Engineers grow pancreatic organoids that mimic the real t... by mleonhard on Tuesday September 14, 2021 @02:47PM (#28529123)

That's all I have at the moment.

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