I don't have a horse in this race, but one difference between cash and monero is that the sheer physical size of cash can cause lots of problems for organized crime[1], to the point that some people advocate for eliminating the $100 bill to make moving large amounts of cash more burdensome [2]. As far as I am aware its irrelevant how much money you are moving in monero until you get up to transaction sizes that effect the price of other monero you hold.

[1] https://freakonomics.com/podcast/still-using-cash/

[2]https://www.nytimes.com/2016/02/22/opinion/getting-rid-of-bi...