As programmers or office based workforce, the worst hazards might be carpal tunnel syndrome, bad back from bad posture and maybe an upset stomach from a bad coffee.

I have known plenty of young guys in the UK who went on these fly in fly out jobs on gas or oil platforms in Australia, as it's a relatively uncomplicated way to get a well paid job (the only good thing about it) due to easy access to Australia, being commonwealth etc. Some of them turned into literal cripples within 2-3 years, others half cripples requiring re education or placement in a less physically demanding job. It's not the same doing this once for a weekend and then classify it as "not so hard" and go out there, work in 100 deg heat or sub freezing temperatures every day, rain, wind etc. It grinds down a body slowly.