Re:Hyperbaric oxygen therapy reverses hallmarks of Alzheimer...
by lthornberry on Monday September 13, 2021 @10:09AM
(#28511695)
This. There is basically zero chance that an ethics review would see this as a case in which a control group is unethical. I have been through plenty of IRB processes.
Resource constraints are a much more plausible explanation - running the study with a control group would cost twice as much (in time as well as money). This is either a pilot to apply for funding to run a better-controlled trial, or it's just not scientifically serious. Both are very plausible, in my experience.
Re:Hyperbaric oxygen therapy reverses hallmarks of Alzheimer...
by jinto36 on Monday September 13, 2021 @09:51PM
(#28519253)
Thanks for the perspective, I have only done data analysis after the data is generated, and never have actually had to deal with an IRB directly for the design of a study.
Resource constraints are a much more plausible explanation - running the study with a control group would cost twice as much (in time as well as money). This is either a pilot to apply for funding to run a better-controlled trial, or it's just not scientifically serious. Both are very plausible, in my experience.