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Re:Biden to mandate coronavirus vaccine for federal workers by angelzen on Thursday September 09, 2021 @04:49PM (#28474479)
CDC says vaccines are only 66 percent effective at preventing Delta infection. As far as I can understand, this means 34% of vaccinated people develop a covid infection. I'm having a hard time squaring this with 'vaccines prevent infection' thesis. Perhaps I'm missing something obvious?

(Yes, I'm aware the fraction is better against severe Delta infection. Yes, I agree 3x reduction is infection rate is a good thing.)

https://www.webmd.com/vaccines/covid-19-vaccine/news/2021082...

Re:Biden to mandate coronavirus vaccine for federal workers by MatteoFrigo on Thursday September 09, 2021 @05:35PM (#28474948)
> this means 34% of vaccinated people develop a covid infection

That's not what "effective" means. It means that if your probability of getting infected without the vaccine is p, your probability of getting infected with the vaccine is .34*p. One way to think about it is that the "ineffectiveness" is the relative risk P[infected|vaccinated]/P[infected|unvaccinated], and effectiveness is 1-ineffectiveness.

A vaccine can be 100% effective even if P[infected] is negligible.

P[infected] is per unit time and does not account for the dynamics of the situation. For example, if the vaccine is not powerful enough to make R<1, then everybody becomes infected eventually regardless of the vaccine.

Re:Biden to mandate coronavirus vaccine for federal workers by angelzen on Thursday September 09, 2021 @05:39PM (#28474985)
Thanks!
Re:Biden to mandate coronavirus vaccine for federal workers by lamontcg on Thursday September 09, 2021 @05:27PM (#28474874)
> CDC says vaccines are only 66 percent effective at preventing Delta infection

WITH A 95% CONFIDENCE INTERVAL OF 26% TO 84%

They only statistically modeled how much their unvaccinated population was already recovered from coronavirus based on estimates of community spread, among other issues with that number.

https://www.cdc.gov/mmwr/volumes/70/wr/mm7034e4.htm

And when you have a CI of something like that size, of course you wind up in the middle of it -- the actual value could very well be closer to 80% due to systematic uncertainties in the modeling.

Re:Biden to mandate coronavirus vaccine for federal workers by disgruntledphd2 on Friday September 10, 2021 @05:11AM (#28479266)
Or 30%, to be fair.
Re:Biden to mandate coronavirus vaccine for federal workers by lamontcg on Friday September 10, 2021 @03:47PM (#28486144)
published on the CDC site today: 77% (74%-80%) VE for pfizer and 92% (89%-93%) VE for moderna. With only some evidence of reduced VE against delta and/or waning in those > 75 years old:

https://www.cdc.gov/mmwr/volumes/70/wr/mm7037e2.htm

Re:Biden to mandate coronavirus vaccine for federal workers by disgruntledphd2 on Saturday September 11, 2021 @09:14AM (#28491721)
That's a very reassuring result, thanks for sharing.

Interesting that moderna continues to do better, and looking forward to seeing the studies VE versus time since vaccination.