How do you manage to cope with overwhelming amounts of uninteresting submissions? I tried to follow via RSS but found it generates to much noise, for that to be useful I would require filtering possibilities in my RSS reader and automatic highlighting for the list of terms on different topics. Any suggestion for a more advanced RSS reader?

I think the feed I use is the front page, but I don’t visit the front page (much) via a browswer. When I click a link in my feed reader (Newsify iOS) it brings me to the comments page of the post.

Newsify is great but it’s been crashing a LOT with iOS 15 beta (not complaining, I know it’s beta). It’s a great reader for iOs devices.

That isn't necessary. That's what hnrss.org is for. It will do searches, and filtering by points.

Subscribe to less? You don't say what exactly you did subscribe to, but there are several services that provide a programmatic feed of submissions with X votes, or Y comments.

Although you could use rss.app to filter the feeds as well.