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A comment on Israel’s Covid-19 boosters are preventing infections, new studies suggest. Parent comment

Re:Israel’s Covid-19 boosters are preventing infections, new... by nradov on Wednesday September 01, 2021 @01:03PM (#28382541)
We don't have the technology to stimulate that accurately in software. It would have to be done using transgenic animal models and/or human tissue cultures. Essentially it would be a form of gain-of-function research, and there are concerns that a lab accident could result in an even more dangerous variant escaping into the wild.
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Re:Israel’s Covid-19 boosters are preventing infections, new... by datameta on Wednesday September 01, 2021 @01:36PM (#28383041)
With ML-assisted drug discovery in, say, kinase inhibitors we search the molecule variation space for test candidates. What stops us from applying this to the protein scale by folding binding sites to discover variant candidates that would be more virulent? I'd like to understand this better.
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Re:Israel’s Covid-19 boosters are preventing infections, new... by nradov on Wednesday September 01, 2021 @01:50PM (#28383269)
Sure you can explore the solution space in software to identify candidates but at some point you have to create a live virus and see how it actually performs.
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