when you target many epitopes, you are shooting at the 10 inch ring; target one epitope of critical function [put one in center of mass] you are shooting the 2 inch ring.

immune systems dont look at everything at once, they find something that sticks and and over trials sharpen the response until highest efficacy of antibody epitope combination is found.

the vaccine is like a laser guided munition, natural immunity is like carpet cluster bombing; both highly effective but in different modalities.