> In conclusion, ADE may occur in people receiving vaccines based on the original Wuhan strain spike sequence (either mRNA or viral vectors) and then exposed to a Delta variant. Although this potential risk has been cleverly anticipated before the massive use of Covid-19 vaccines6, the ability of SARS-CoV-2 antibodies to mediate infection enhancement in vivo has never been formally demonstrated. However, although the results obtained so far have been rather reassuring1, to the best of our knowledge ADE of Delta variants has not been specifically assessed. Since our data indicate that Delta variants are especially well recognized by infection enhancing antibodies targeting the NTD, the possibility of ADE should be further investigated as it may represent a potential risk for mass vaccination during the current Delta variant pandemic. In this respect, second generation vaccines7 with spike protein formulations lacking structurally-conserved ADE-related epitopes should be considered.
This isn't saying anything other than "hey maybe this should be something to look out for though it looks like it was accounted for in the original vaccine development".
Leave the science to the scientists, virologists, and medical professionals. Stop insinuating that there is some sort of scary unknown danger here.
You don't know what you're talking about, there is 0 evidence suggesting that ADE will be an issue, and even the study you cited states "Although this potential risk has been cleverly anticipated before the massive use of Covid-19 vaccines..." which, big surprise, means the pharmaceutical companies creating these vaccines have anticipated this exact thing.
> Of those 16 to 17 deaths, the vast majority will be people with comorbidities. People with comorbidities don't have as many years to live as healthy people of the same age, with or without Covid.
Ok? And? So don't get a vaccine because you found some study that says something that Moderna, Pfizer, AstraZeneca, and the entire global health community somehow didn't notice or account for and it'll cause some big scary serious illness problem? Die 5 years prematurely because the vaccine has some unknown and unscientific probability of killing you when we know for a fact that the vaccine will reduce the severity of symptoms occurring due to COVID-19 if you even contract the disease?
But let me guess. You're just "asking questions" right?
Stop.
Lots of scientists with qualifications relevant to the debate have been critical of the official position.
> But let me guess. You're just "asking questions" right?
Wrong guess. If I was asking questions, I would have put a question mark in there.
My point stands: We do not know how the vaccines will react with new variants.
We also do not know what reactions may result from new variants + eating chicken, or wearing green shirts, or exercise.
Better play it safe I guess.
And, to use your phrasing, we do not know how _unvaccinated_ people will react to the new strains either. We do, however, know that the vaccines seem to offer a high degree of protection.
In 2019 almost a quarter of NY's population was over 60 (https://www.statista.com/statistics/911456/new-york-populati...)
In 2019, 34% were overweight and 22% were obese (https://www1.nyc.gov/site/doh/health/health-topics/obesity.p...)
Also Cuomo literally sent people infected with coronavirus into care homes.
> Also Cuomo literally sent people infected with coronavirus into care homes.
Funny the Democrats actually impeached one of their own unethical asshole “leader”. Wonder when the Republicans will catch up and show us those family values.
There is a very strong correlation between GDP and life expectancy, especially in developing nations.
The money would have been better spent improving countries' health systems, so hospitals wouldn't get swamped.
It's absolutely insane the way the world reacted to this virus. I consider it the first global mass hysteria.
Of those 16 to 17 deaths, the vast majority will be people with comorbidities. People with comorbidities don't have as many years to live as healthy people of the same age, with or without Covid.
On the other hand, we do not know how vaccinated immune systems will interact with an evolving virus. There is a study suggesting that ADE might be a higher risk with the Delta variant ("However, the emergence of SARS-CoV-2 variants may tip the scales in favor of infection enhancement. Our structural and modeling data suggest that it might be indeed the case for Delta variants": https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351274/)
If ADE becomes a significant issue with Delta, or the next variant to emerge we will have a scenario where people vaccinated against the Alpha ("Wuhan") strain will develop more serious illness. Imagine the shit that will hit the fan if that happens XD