Well, you wouldn't say someone with AIDS had problems with "Stress, bad diet, lack of social interaction", for example. Yet Dr. Nancy Klimas got interested in CFS patients when she found they were sicker than her AIDS patients. (Of course, outcomes for AIDS patients are far worse!)
Symptoms are as real as the patient feels it. It's not over until they feel cured. Anybody who's struggled with something outside their power knows that strength of will can work miracles but only get you so far.