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A comment on The Coronavirus Is Here Forever. Parent comment

Re:The Coronavirus Is Here Forever by AdamN on Monday August 23, 2021 @12:46PM (#28278612)
Keep in mind the initial dose is highly relevant to the impact of the virus in your body. There's a big difference between getting a single virus, enough to cause an infection, and enough to be highly overwhelmed before your immune system kicks in.
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Re:The Coronavirus Is Here Forever by nradov on Monday August 23, 2021 @01:07PM (#28278900)
There is no real scientific evidence that disease severity is correlated with initial viral dose. It's a plausible hypothesis but so far due to ethical concerns no one has done the human challenge trials that would be necessary to settle that issue.
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Re:The Coronavirus Is Here Forever by AdamN on Monday August 23, 2021 @02:26PM (#28279960)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8045461/

This is a common attribute of infections and is really more of a math issue than anything SARS-specific. The bigger the initial dose, the sooner it will get to the impact stage, and the less prepared your immune system will be at that time.

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