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A comment on FDA Approves First Covid-19 Vaccine. Parent comment

Re:FDA Approves First Covid-19 Vaccine by criticaltinker on Monday August 23, 2021 @12:37PM (#28278479)
Yes this is a great point. The primary concerns & warnings are generally around vaccine induced immune escape, which is a realistic consequence of indiscriminate compulsory mass vaccination [1][2][3][4][5][6].

That said, there is general consensus in the literature that the vaccines are mostly safe for adults in the short term. However for certain sub-populations (eg pediatrics and pregnant women) there isn't enough evidence yet from clinical trials and longitudinal studies to conclude with certainty that the benefits of compulsory mass vaccination outweigh the risks.

[1] Risk of rapid evolutionary escape from biomedical interventions targeting SARS-CoV-2 spike protein https://pubmed.ncbi.nlm.nih.gov/33909660/

[2] Can we predict the limits of SARS-CoV-2 variants and their phenotypic consequences? https://www.gov.uk/government/publications/long-term-evoluti...

[3] Why does drug resistance readily evolve but vaccine resistance does not? https://royalsocietypublishing.org/doi/pdf/10.1098/rspb.2016...

[4] The adaptive evolution of virulence: a review of theoretical predictions and empirical tests https://pubmed.ncbi.nlm.nih.gov/26302775/

[5] Imperfect Vaccination Can Enhance the Transmission of Highly Virulent Pathogens https://journals.plos.org/plosbiology/article?id=10.1371%2Fj...

[6] Necessity of COVID-19 vaccination in previously infected individuals https://www.medrxiv.org/content/10.1101/2021.06.01.21258176v...

[ Parent | on HN ]
Re:FDA Approves First Covid-19 Vaccine by criticaltinker on Monday August 23, 2021 @04:50PM (#28281740)
Lots of down-votes and no replies tells me this is striking some nerves - anyone care to articulate why you disagree with or do not support these statements?
[ Parent | on HN ]
Re:FDA Approves First Covid-19 Vaccine by yupper32 on Monday August 23, 2021 @05:10PM (#28282002)
Almost no one on HN is qualified to take a group of medical journal articles/research papers and form an accurate opinion on the subject.

In fact, trying to do so for most on this forum would probably result in inaccurate views due to misunderstanding the articles and papers.

So people probably downvoted because you have a view on the subject, but no one is qualified to back or oppose it. And we don't know who you are, so how are we supposed to vet your view, or even begin to have a conversation about it?

I didn't downvote (or upvote), but that's my guess.

[ Parent | on HN ]